{"id":"msh6","name":"MSH6","symbol":"MSH6","route":"/targets/msh6/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7329","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000116062","uniprot":"https://www.uniprot.org/uniprotkb/P52701/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P52701","open-targets":"https://platform.opentargets.org/target/ENSG00000116062","civic":"https://civicdb.org/genes/2956/summary","oncokb":"https://www.oncokb.org/gene/MSH6","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=MSH6","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=MSH6","depmap":"https://depmap.org/portal/gene/MSH6?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000116062-MSH6","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/2956","omim":"https://www.omim.org/entry/600678"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":["paper-abida-msi-prostate-checkpoint-blockade-jama-oncol-2019","paper-hu-mismatch-repair-deficiency-pancreatic-adenocarcinoma-ccr-2018","paper-pritchard-complex-msh2-msh6-hypermutated-prostate-nat-commun-2014","paper-moreira-lynch-syndrome-identification-jama-2012"],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}