{"id":"mgmt-protein","name":"MGMT (O6-methylguanine-DNA methyltransferase)","symbol":"MGMT","route":"/targets/mgmt-protein/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7059","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000170430","uniprot":"https://www.uniprot.org/uniprotkb/P16455/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P16455","chembl":"https://www.ebi.ac.uk/chembl/explore/target/CHEMBL2864","open-targets":"https://platform.opentargets.org/target/ENSG00000170430","civic":"https://civicdb.org/genes/4255/summary","oncokb":"https://www.oncokb.org/gene/MGMT","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=MGMT","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=MGMT","depmap":"https://depmap.org/portal/gene/MGMT?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000170430-MGMT","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/4255","omim":"https://www.omim.org/entry/156569"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}