{"id":"il11ra","name":"IL-11 receptor alpha","symbol":"IL11RA","route":"/targets/il11ra/","asOf":"2026-09-04","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5967","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000137070","uniprot":"https://www.uniprot.org/uniprotkb/Q14626/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/Q14626","chembl":"https://www.ebi.ac.uk/chembl/explore/target/CHEMBL2050","open-targets":"https://platform.opentargets.org/target/ENSG00000137070","civic":"https://civicdb.org/genes/3590/summary","oncokb":"https://www.oncokb.org/gene/IL11RA","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=IL11RA","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=IL11RA","depmap":"https://depmap.org/portal/gene/IL11RA?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000137070-IL11RA","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/3590","omim":"https://www.omim.org/entry/600939"}],"products":[{"id":"oprelvekin","name":"Oprelvekin","status":"withdrawn","modality":"Recombinant interleukin-11, subcutaneous injection","route":"/drugs/oprelvekin/"}],"trials":[{"id":"nct00493181","name":"Interleukin 11, Thrombocytopenia, Imatinib in Chronic Myelogenous Leukemia (CML) Patients","nct":"NCT00493181","phase":"2","status":"completed"},{"id":"nct00004157","name":"Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors","nct":"NCT00004157","phase":"2","status":"completed"}],"pathways":[],"companies":["pfizer"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}