{"id":"htr3a","name":"5-HT3 receptor (HTR3A)","symbol":"HTR3A","route":"/targets/htr3a/","asOf":"2026-09-04","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5297","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000166736","uniprot":"https://www.uniprot.org/uniprotkb/P46098/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P46098","chembl":"https://www.ebi.ac.uk/chembl/explore/target/CHEMBL1899","open-targets":"https://platform.opentargets.org/target/ENSG00000166736","civic":"https://civicdb.org/genes/3359/summary","oncokb":"https://www.oncokb.org/gene/HTR3A","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=HTR3A","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=HTR3A","depmap":"https://depmap.org/portal/gene/HTR3A?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000166736-HTR3A","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/3359","omim":"https://www.omim.org/entry/182139"}],"products":[{"id":"dolasetron","name":"Dolasetron","status":"established","modality":"Oral 5-HT3 receptor antagonist antiemetic","route":"/drugs/dolasetron/"}],"trials":[],"pathways":[],"companies":[],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}