{"id":"ednra","name":"EDNRA","symbol":"EDNRA","route":"/targets/ednra/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3179","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000151617","uniprot":"https://www.uniprot.org/uniprotkb/P25101/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P25101","open-targets":"https://platform.opentargets.org/target/ENSG00000151617","civic":"https://civicdb.org/genes/1909/summary","oncokb":"https://www.oncokb.org/gene/EDNRA","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=EDNRA","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=EDNRA","depmap":"https://depmap.org/portal/gene/EDNRA?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000151617-EDNRA","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/1909","omim":"https://www.omim.org/entry/131243"}],"products":[{"id":"atrasentan","name":"Atrasentan","status":"withdrawn","modality":"small molecule","route":"/drugs/atrasentan/"},{"id":"zibotentan","name":"Zibotentan","status":"withdrawn","modality":"small molecule","route":"/drugs/zibotentan/"}],"trials":[{"id":"swog-s0421-atrasentan","name":"SWOG S0421","nct":"NCT00134056","phase":"3","status":"negative"},{"id":"enthuse-m1-zibotentan","name":"ENTHUSE M1","nct":"NCT00554229","phase":"3","status":"negative"}],"pathways":[],"companies":["abbvie","astrazeneca"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}