{"id":"cnr1","name":"Cannabinoid receptor 1","symbol":"CNR1","route":"/targets/cnr1/","asOf":"2026-09-04","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2159","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000118432","uniprot":"https://www.uniprot.org/uniprotkb/P21554/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P21554","chembl":"https://www.ebi.ac.uk/chembl/explore/target/CHEMBL218","open-targets":"https://platform.opentargets.org/target/ENSG00000118432","civic":"https://civicdb.org/genes/1268/summary","oncokb":"https://www.oncokb.org/gene/CNR1","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=CNR1","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=CNR1","depmap":"https://depmap.org/portal/gene/CNR1?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000118432-CNR1","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/1268","omim":"https://www.omim.org/entry/114610"}],"products":[{"id":"dronabinol","name":"Dronabinol","status":"established","modality":"Oral small-molecule synthetic cannabinoid","route":"/drugs/dronabinol/"},{"id":"nabilone","name":"Nabilone","status":"established","modality":"Oral small-molecule synthetic cannabinoid","route":"/drugs/nabilone/"}],"trials":[{"id":"nct02802540","name":"Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients","nct":"NCT02802540","phase":"2/3"},{"id":"nct06731894","name":"Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors","nct":"NCT06731894","phase":"2","status":"recruiting"}],"pathways":[],"companies":["abbvie","eli-lilly","insys-therapeutics"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}