{"id":"cdkn2a","name":"CDKN2A","symbol":"CDKN2A","route":"/targets/cdkn2a/","asOf":"2026-09-23","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1787","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000147889","uniprot":"https://www.uniprot.org/uniprotkb/P42771/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P42771","open-targets":"https://platform.opentargets.org/target/ENSG00000147889","civic":"https://civicdb.org/genes/1029/summary","oncokb":"https://www.oncokb.org/gene/CDKN2A","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=CDKN2A","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=CDKN2A","depmap":"https://depmap.org/portal/gene/CDKN2A?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000147889-CDKN2A","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/1029","omim":"https://www.omim.org/entry/600160"}],"products":[],"trials":[],"pathways":[],"companies":[],"keyPapers":["paper-cowzer-biliary-targeted-therapy-determinants-ccr-2026","paper-suryavanshi-indian-gallbladder-genomics-jco-go-2025","paper-giraldo-gallbladder-msk-impact-ccr-2022","paper-caps-consortium-surveillance-recommendations-gut-2020","paper-jiang-fuscc-tnbc-landscape-cancer-cell-2019","paper-yurgelun-germline-second-hits-resected-pancreatic-genet-med-2019","paper-singhi-targeted-genome-profiling-3594-pdac-gastroenterology-2019","paper-hu-germline-mutations-pancreatic-cancer-risk-jama-2018","paper-qian-driver-genes-outcomes-resected-pancreatic-jama-oncol-2018","paper-chapuy-molecular-subtypes-dlbcl-nat-med-2018","paper-shindo-germline-sporadic-pancreatic-jco-2017","paper-tcga-pancreatic-integrated-characterisation-cancer-cell-2017","paper-notta-punctuated-evolution-pancreatic-nature-2016","paper-javle-biliary-ngs-cancer-2016","paper-bailey-molecular-subtypes-pancreatic-nature-2016","paper-roberts-familial-pancreatic-whole-genome-cancer-discov-2016","paper-springer-pancreatic-cyst-molecular-classification-gastroenterology-2015","paper-skoulidis-kras-co-mutation-subsets-cancer-discov-2015","paper-waddell-whole-genomes-pancreatic-nature-2015","paper-tcga-lung-squamous-nature-2012","paper-biankin-pancreatic-exomes-axon-guidance-nature-2012","paper-kanda-panin-1-somatic-mutations-gastroenterology-2012","paper-jones-pancreatic-core-pathways-science-2008"],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}