{"id":"ccr4","name":"CCR4","symbol":"CCR4","route":"/targets/ccr4/","asOf":"2026-09-08","xrefs":[{"hgnc":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1605","ensembl":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000183813","uniprot":"https://www.uniprot.org/uniprotkb/P51679/entry","alphafold-db":"https://alphafold.ebi.ac.uk/entry/P51679","chembl":"https://www.ebi.ac.uk/chembl/explore/target/CHEMBL2414","open-targets":"https://platform.opentargets.org/target/ENSG00000183813","civic":"https://civicdb.org/genes/1233/summary","oncokb":"https://www.oncokb.org/gene/CCR4","cosmic":"https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=CCR4","cbioportal":"https://www.cbioportal.org/results/mutations?cancer_study_list=msk_impact_2017&gene_list=CCR4","depmap":"https://depmap.org/portal/gene/CCR4?tab=overview","human-protein-atlas":"https://www.proteinatlas.org/ENSG00000183813-CCR4","ncbi-gene":"https://www.ncbi.nlm.nih.gov/gene/1233","omim":"https://www.omim.org/entry/604836"}],"products":[{"id":"mogamulizumab","name":"Mogamulizumab","status":"approved","modality":"Defucosylated anti-CCR4 monoclonal antibody","route":"/drugs/mogamulizumab/"}],"trials":[{"id":"mavoric","name":"MAVORIC","nct":"NCT01728805","phase":"3","status":"positive"},{"id":"nct04930653","name":"Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma","nct":"NCT04930653","phase":"2","status":"recruiting"}],"pathways":[],"companies":["kyowa-kirin"],"keyPapers":[],"hotspots":[],"openQuestions":[],"assays":[],"resistance":[],"licence":"CC BY-NC 4.0, attribution to OnCo (https://onco.cc); commercial use needs a licence"}