# Thomas A. Hope

Source: https://onco.cc/people/thomas-hope/  
OnCo record `thomas-hope` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Nuclear medicine physician who led the trials that got PSMA PET approved in the United States.

## Summary

Thomas Hope is Professor of Radiology and Chief of Nuclear Medicine at UCSF, within the UCSF Helen Diller Family Comprehensive Cancer Center. A nuclear medicine physician specialising in PSMA PET and theranostics, his prospective studies of 68Ga-PSMA-11 PET at UCSF and UCLA supported the first FDA approval of PSMA PET in the United States in 2020. His papers include a JAMA Oncology multicentre prospective phase 3 imaging trial of the diagnostic accuracy of 68Ga-PSMA-11 PET for pelvic nodal metastasis before radical prostatectomy and a JAMA Oncology prospective single-arm trial assessing its accuracy in localising recurrent prostate cancer. He leads theranostics research and PSMA radioligand dosimetry work in prostate cancer.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Professor of Radiology; Chief of Nuclear Medicine, UCSF
- Specialisms: Nuclear medicine; PSMA PET; Theranostics

## Sources

- UCSF profile: https://profiles.ucsf.edu/search/?searchtype=people&searchfor=Thomas%20A.%20Hope
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Hope%20TA%5BAuthor%5D
- Google Scholar: https://scholar.google.com/scholar?q=Thomas%20A.%20Hope

## Connected records

- cancers: [Prostate cancer](https://onco.cc/cancers/prostate/)
- technologies: [PET (positron emission tomography)](https://onco.cc/technologies/pet/), [PSMA PET](https://onco.cc/technologies/psma-pet/), [Radioligand therapy (beta emitters)](https://onco.cc/technologies/radioligand-therapy/)
- targets: [PSMA](https://onco.cc/targets/psma/)
- institutions: [UCSF Helen Diller Family Comprehensive Cancer Center](https://onco.cc/institutions/ucsf/)
- trials: [PSMA-PreRP](https://onco.cc/trials/psma-prerp/)
- key papers: [Diagnostic accuracy of 68Ga-PSMA-11 PET for pelvic nodal metastasis detection prior to radical prostatectomy and pelvic lymph node dissection: a multicenter prospective phase 3 imaging trial](https://onco.cc/key-papers/paper-psma-prerp-hope-jama-oncol-2021/)

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