# Stanley R. Riddell

Source: https://onco.cc/people/stanley-riddell/  
OnCo record `stanley-riddell` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Adoptive T-cell therapy pioneer whose defined-composition CAR-T work led to lisocabtagene maraleucel.

## Summary

Stanley Riddell is Professor in the Translational Science and Therapeutics Division at Fred Hutchinson Cancer Center. An immunologist specialising in T-cell immunotherapy, CAR-T and adoptive cell transfer, he pioneered antigen-specific T-cell transfer for viral infections after transplant and later CD19 CAR-T with defined CD4:CD8 ratios, the basis of Juno Therapeutics and of lisocabtagene maraleucel (Breyanzi). His papers include the report of CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B-cell ALL and the Science paper on restoring viral immunity in immunodeficient humans by adoptive transfer of T cell clones. He now works on CAR design and solid-tumour targets such as ROR1, with relevance to lymphoma and leukaemia.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Professor, Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center
- Specialisms: T-cell immunotherapy; CAR-T; Adoptive cell transfer

## Sources

- Fred Hutch faculty directory: https://www.fredhutch.org/en/faculty-lab-directory.html?q=Stanley%20R.%20Riddell
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Riddell%20SR%5BAuthor%5D
- Google Scholar: https://scholar.google.com/scholar?q=Stanley%20R.%20Riddell

## Connected records

- cancers: [Acute lymphoblastic leukaemia](https://onco.cc/cancers/all-leukemia/), [Chronic lymphocytic leukaemia](https://onco.cc/cancers/cll/), [Diffuse large B-cell lymphoma](https://onco.cc/cancers/dlbcl/)
- technologies: [CAR-T cell therapy](https://onco.cc/technologies/car-t/)
- targets: [CD19](https://onco.cc/targets/cd19/), [ROR1](https://onco.cc/targets/ror1/)
- drugs: [Lisocabtagene maraleucel](https://onco.cc/drugs/lisocabtagene-maraleucel/)
- institutions: [Fred Hutchinson Cancer Center](https://onco.cc/institutions/fred-hutch/)
- journals: [Journal of Clinical Investigation](https://onco.cc/journals/jci/)

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