# Segmentectomy (sublobar resection)

Source: https://onco.cc/terms/segmentectomy/  
OnCo record `segmentectomy` (Term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Removing only a segment or wedge of a lung lobe rather than the whole lobe, sparing breathing capacity.

## Summary

Once reserved for patients who could not tolerate lobectomy, anatomical segmentectomy became a standard option for peripheral tumours ≤2 cm after JCOG0802 (2022) showed better overall survival and CALGB 140503 showed non-inferior disease-free survival. Wedge resection is a non-anatomical version with less lymph node clearance. The same lung-sparing logic drives lung-sparing surgery in mesothelioma and parenchyma-sparing liver resection.

## Fields

- Kind: Term
- Last checked: 2026-09-09
- Also known as: sublobar resection; wedge resection; segmentectomies

## Notes

- Lung cancer: NICE NG122 (1.5.5) says that for people with stage 1 to 2a disease who decline lobectomy or in whom it is contraindicated, offer radical radiotherapy with stereotactic ablative radiotherapy or sublobar resection. NICE's rationale says both give better survival than conventionally fractionated radiotherapy, and that the evidence does not show which of the two is better, which is why the choice is a shared one rather than a rule.

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/Segmental_resection
- Wikipedia: https://en.wikipedia.org/wiki/Segmental_resection
- NICE NG122: lung cancer, management: https://www.nice.org.uk/guidance/ng122/chapter/Management

## Connected records

- terms: [Lobectomy](https://onco.cc/terms/lobectomy/), [Sublobar resection (segmentectomy and wedge)](https://onco.cc/terms/sublobar-resection/)
- cancers: [Lung cancer (all types)](https://onco.cc/cancers/lung-cancer/), [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Resectable stage I to III non-small-cell lung cancer](https://onco.cc/cancers/resectable-nsclc/)
- fronts: [Surgery & Interventional](https://onco.cc/fronts/surgery/)
- trials: [CALGB 140503 (Alliance)](https://onco.cc/trials/calgb-140503/), [JCOG0802 / WJOG4607L](https://onco.cc/trials/jcog0802/)

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