# Pier Giuseppe Pelicci

Source: https://onco.cc/people/pier-giuseppe-pelicci/  
OnCo record `pier-giuseppe-pelicci` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Molecular oncologist who characterised PML-RARα in acute promyelocytic leukaemia and studies cancer stem cells.

## Summary

Pier Giuseppe Pelicci is Director of Research at IEO, the European Institute of Oncology, in Milan and Professor at the University of Milan. A molecular oncologist, his specialisms are cancer biology, leukaemia, cancer stem cells and epigenetics. He characterised PML-RARα in acute promyelocytic leukaemia, and his work on that disease, on p66Shc and on stem cell self-renewal made IEO a leading basic research centre. His papers include a Cell Reports study of how p53 loss in breast cancer leads to Myc activation and increased cell plasticity, a study of humanised mice failing to reject human acute myeloid leukaemia cells, and a Nature Communications paper showing caloric restriction expands druggable LSD1-dependent cancer stem cells. His publications are listed on PubMed.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Director of Research, IEO; Professor, University of Milan
- Specialisms: Cancer biology; Leukaemia; Cancer stem cells; Epigenetics

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Pelicci%20PG%5BAuthor%5D%20leukemia

## Connected records

- cancers: [Acute myeloid leukaemia](https://onco.cc/cancers/aml/)
- institutions: [Fondazione AIRC per la ricerca sul cancro](https://onco.cc/institutions/airc/), [IEO (European Institute of Oncology)](https://onco.cc/institutions/ieo-milan/)

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