# Optellum Virtual Nodule Clinic

Source: https://onco.cc/drugs/optellum-virtual-nodule-clinic/  
OnCo record `optellum-virtual-nodule-clinic` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The first AI cleared to estimate how likely a lung nodule on a CT scan is to be cancer, helping doctors decide who needs a biopsy and who can wait.

## Summary

Optellum (Oxford, UK) received FDA 510(k) clearance in March 2021 for the Virtual Nodule Clinic, the first AI decision-support software for lung cancer diagnosis, and is CE-marked. The LCP score was validated on the NLST and other cohorts and, in reader studies, improved clinicians' discrimination of benign from malignant nodules; the product is used in NHS trusts and US health systems to run nodule clinics and to prioritise early biopsy of high-risk nodules. As lung screening programmes expand, most nodules found are benign, and the value of such tools lies in reducing unnecessary procedures without delaying cancer diagnoses.

## Fields

- Kind: Treatment
- Status: approved
- Last checked: 2026-09-10
- Tags: test
- Brand: Virtual Nodule Clinic
- Modality: AI lung nodule malignancy prediction software (CT)
- Mechanism: Deep-learning Lung Cancer Prediction (LCP) score on CT images of indeterminate pulmonary nodules, combined with nodule tracking software to support clinic decision-making.
- Approvals: US 2021: 510(k) clearance: AI decision support for indeterminate pulmonary nodules; EU 2020: CE mark

## Notes

- What a result means: a low malignancy score supports watchful CT follow-up of a nodule; a high score speeds up PET scan or biopsy.

## Sources

- Optellum: https://optellum.com

## Connected records

- technologies: [AI in radiology](https://onco.cc/technologies/radiology-ai-screening/), [CT (computed tomography)](https://onco.cc/technologies/ct/), [Low-dose CT lung screening](https://onco.cc/technologies/low-dose-ct-screening/), [Sybil (MIT/MGH lung cancer risk from CT)](https://onco.cc/technologies/sybil/)
- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- companies: [Optellum](https://onco.cc/companies/optellum/)
- terms: [Pulmonary nodule](https://onco.cc/terms/pulmonary-nodule/)

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