# A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Source: https://onco.cc/trials/nct04658862/  
OnCo record `nct04658862` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial testing Cetrelimab in bladder & urothelial cancer, active and no longer recruiting.

## Summary

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder is a phase 3 interventional study registered as NCT04658862, led by Janssen Research & Development, and active but no longer recruiting on the registry. Official title: A Phase 3, Multi-centre, Randomised Study Evaluating Efficacy of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-Invasive Urothelial Carcinoma (MIBC) of the Bladder Who Are Not Receiving Radical Cystectomy. Planned enrolment is 518 participants (actual). The study started in 2020-12-07 and primary completion is expected in 2026-12-30. No results have been posted on ClinicalTrials.gov.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-11
- Also known as: SunRISe-2
- Tags: ctgov-ingest
- Registry id: NCT04658862
- Phase: 3
- Setting: A Phase 3, Multi-center, Randomized Study Evaluating Efficacy of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-Invasive Urothelial Carcinoma (MIBC) of the Bladder Who Are Not Receiving Radical Cystectomy
- Sponsor: Janssen Research & Development
- Enrolled: 518

## Sources

- ClinicalTrials.gov NCT04658862: https://clinicaltrials.gov/study/NCT04658862

## Connected records

- cancers: [Bladder & urothelial cancer](https://onco.cc/cancers/urothelial/), [Muscle-invasive and advanced bladder cancer](https://onco.cc/cancers/muscle-invasive-bladder-cancer/)
- drugs: [Cetrelimab](https://onco.cc/drugs/cetrelimab/)
- companies: [Johnson & Johnson](https://onco.cc/companies/johnson-johnson/)

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