# Malachi Griffith

Source: https://onco.cc/people/malachi-griffith/  
OnCo record `malachi-griffith` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Co-created CIViC, the open database of what cancer mutations mean, and the pVACtools neoantigen pipeline.

## Summary

Malachi Griffith is Associate Professor of Medicine and Genetics and Assistant Director of the McDonnell Genome Institute at Siteman Cancer Center, Washington University. With Obi Griffith he co-created CIViC, the open community database of what cancer mutations mean, and the pVACtools neoantigen prediction pipeline. His selected paper describes CIViC as a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. He now designs personalised neoantigen vaccine trials at WashU and continues to work on clinical genomics.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Associate Professor of Medicine and Genetics; Assistant Director, McDonnell Genome Institute
- Specialisms: Clinical genomics; CIViC knowledge base; Neoantigen prediction

## Sources

- Griffith lab: https://griffithlab.org
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Griffith%20M%5BAuthor%5D

## Connected records

- technologies: [Comprehensive genomic profiling](https://onco.cc/technologies/cgp/), [Personalised neoantigen (mRNA) vaccines](https://onco.cc/technologies/neoantigen-mrna-vaccine/)
- institutions: [Siteman Cancer Center, Washington University](https://onco.cc/institutions/wustl-siteman/)
- terms: [Neoantigen](https://onco.cc/terms/neoantigen/)
- journals: [Nature Genetics](https://onco.cc/journals/nature-genetics/)

---
JSON: https://onco.cc/api/v1/entities/malachi-griffith.json