# Lumicell

Source: https://onco.cc/companies/lumicell/  
OnCo record `lumicell` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

MIT spin-out whose Lumisight dye and imaging system show leftover breast cancer in the lumpectomy cavity before the operation ends.

## Summary

Lumicell, based in Newton, Massachusetts, and founded in 2008, is the MIT spin-out whose Lumisight dye and imaging system show leftover breast cancer in the lumpectomy cavity before the operation ends. Its pegulicianine, sold as Lumisight, and the Lumicell Direct Visualization System were approved by the FDA in April 2024 after the INSITE trial, making the combination the first optical imaging agent approved for breast cancer surgery. OnCo links it to HR-positive, triple-negative and HER2-positive breast cancer, fluorescence-guided surgery and optical imaging, and to the pegulicianine record. Whether intraoperative imaging reduces re-operations enough to justify its cost and time is the open question. Pegulicianine has its own page.

## Fields

- Kind: Company
- Last checked: 2026-09-10
- HQ: Newton, MA
- Type: imaging
- Website: https://www.lumicell.com

## Sources

- Official website: https://www.lumicell.com

## Connected records

- cancers: [HER2-positive breast cancer](https://onco.cc/cancers/breast-her2-positive/), [HR-positive / HER2-negative breast cancer](https://onco.cc/cancers/breast-hr-positive/), [Triple-negative breast cancer (TNBC)](https://onco.cc/cancers/tnbc/)
- fronts: [Imaging](https://onco.cc/fronts/imaging/), [Surgery & Interventional](https://onco.cc/fronts/surgery/)
- technologies: [Fluorescence-guided surgery](https://onco.cc/technologies/fluorescence-guided-surgery/), [Intraoperative fluorescence and Cerenkov imaging systems (SPY, Firefly, LumiSystem, LightPath)](https://onco.cc/technologies/intraoperative-fluorescence-imaging-systems/), [Optical & fluorescence imaging](https://onco.cc/technologies/optical-imaging/)
- drugs: [Pegulicianine](https://onco.cc/drugs/pegulicianine/)
- trials: [Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers](https://onco.cc/trials/nct02584244/), [INSITE](https://onco.cc/trials/insite/)

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