# You Lu

Source: https://onco.cc/people/lu-you/  
OnCo record `lu-you` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Ran the first clinical trial of CRISPR-edited T cells in humans, in patients with lung cancer.

## Summary

You Lu is Professor of Thoracic Oncology at West China Hospital, Sichuan University, where he leads thoracic oncology. He ran the first clinical trial of CRISPR-edited T cells in humans, a first-in-human study of PD-1-edited T cells in patients with lung cancer, alongside research in lung cancer radiotherapy and immunotherapy. His publications include the report on the safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. His interests are lung cancer, radiation oncology, CRISPR-edited and engineered T cells, and immunotherapy.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Professor of Thoracic Oncology, West China Hospital, Sichuan University
- Specialisms: Lung cancer; Radiation oncology; CRISPR-edited T cells; Immunotherapy

## Sources

- West China Hospital: https://www.wchscu.cn
- PubMed author search: https://pubmed.ncbi.nlm.nih.gov/?term=Lu%20Y%5BAuthor%5D%20West%20China%20CRISPR%20PD-1%20T%20cells

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- technologies: [CAR-T cell therapy](https://onco.cc/technologies/car-t/), [CRISPR functional genomics](https://onco.cc/technologies/crispr-screens/), [TCR-T cell therapy](https://onco.cc/technologies/tcr-t/)
- targets: [PD-1](https://onco.cc/targets/pd1/)
- institutions: [West China Hospital, Sichuan University](https://onco.cc/institutions/west-china/)

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JSON: https://onco.cc/api/v1/entities/lu-you.json