# IAH0968

Source: https://onco.cc/drugs/iah0968/  
OnCo record `iah0968` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

IAH0968 is an experimental small-molecule drug from SUNHO（China）BioPharmaceutical CO. in phase 3 trials for gastric & gastro-oesophageal junction cancer, aimed at HER2.

## Summary

IAH0968 is a small-molecule drug developed by SUNHO（China）BioPharmaceutical CO.. Its target is HER2 (the sponsor names HER2). ClinicalTrials.gov describes the intervention as: Experimental：IAH0968 15 mg/kg on Day 1 of each 3-week cycle as an IV infusion. Drug: Oxaliplatin 130 mg/m\^2 on Day 1 of each 3-week cycle over 2 hours as an IV infusion, administered as part of CAPOX chemotherapy regimen. Drug: Capecitabin. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, including the phase 3 study NCT06504732 (To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer), in gastric & gastro-oesophageal junction cancer. The largest, NCT06504732, plans to enrol 574 participants with primary completion expected 2028-07. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.

## Fields

- Kind: Treatment
- Status: phase-3
- Last checked: 2026-09-11
- Tags: pipeline; ctgov-ingest
- Modality: monoclonal antibody (anti-HER2, per the sponsor's pipeline page; registered as a drug on ClinicalTrials.gov)
- Mechanism: Small-molecule drug directed at HER2, as stated in the ClinicalTrials.gov intervention record; the detailed mechanism is not stated.

## Sources

- ClinicalTrials.gov: trials of IAH0968: https://clinicaltrials.gov/search?intr=IAH0968

## Connected records

- cancers: [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/)
- targets: [HER2](https://onco.cc/targets/her2/)
- companies: [Hutchmed](https://onco.cc/companies/hutchmed/), [SunHo Biopharmaceutical](https://onco.cc/companies/sunho-biopharmaceutical/)
- trials: [To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer](https://onco.cc/trials/nct06504732/)

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JSON: https://onco.cc/api/v1/entities/iah0968.json