# Flatiron Health and Foundation Medicine Clinico-Genomic Database

Source: https://onco.cc/collections/flatiron-foundation-cgdb/  
OnCo record `flatiron-foundation-cgdb` (Collection). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Real-world evidence at scale: what happened to patients with a given genomic profile on a given treatment.

## Summary

The Flatiron Health and Foundation Medicine Clinico-Genomic Database is real-world evidence at scale: it records what happened to patients with a given genomic profile on a given treatment. It links electronic health record outcomes with comprehensive genomic profiles for more than 100,000 US cancer patients and is used for external control arms, label expansions and training multimodal outcome models. Access is commercial or by research agreement, and the database is maintained by Flatiron Health, part of Roche, with Foundation Medicine, so the company records for Foundation Medicine (Roche) and Roche / Genentech are linked. The collection is referenced by the roadmaps on AI in the oncology clinic, AI in oncology and trial modernisation.

## Fields

- Kind: Collection
- Last checked: 2026-09-08
- Tags: data; real-world
- URL: https://flatiron.com/
- Holds: Linked EHR outcomes and comprehensive genomic profiles for >100,000 US cancer patients.
- Licence: Commercial / research access

## Sources

- Flatiron Health and Foundation Medicine Clinico-Genomic Database (page moved; nearest live section): https://flatiron.com/

## Connected records

- companies: [Foundation Medicine (Roche)](https://onco.cc/companies/foundation-medicine/), [Roche / Genentech](https://onco.cc/companies/roche-genentech/)
- roadmaps: [AI in oncology roadmap: pattern readers → foundation models → agents in the workflow](https://onco.cc/roadmaps/ai-oncology-roadmap/), [AI in the oncology clinic: from narrow cleared tools to multimodal decision support](https://onco.cc/roadmaps/ai-oncology-clinic/), [Trial modernisation roadmap: the randomised trial → platforms and adaptive designs → decentralised, pragmatic and always-on](https://onco.cc/roadmaps/trial-modernisation-roadmap/)

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JSON: https://onco.cc/api/v1/entities/flatiron-foundation-cgdb.json