# Eric R. Fearon

Source: https://onco.cc/people/eric-fearon/  
OnCo record `eric-fearon` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Co-author of the Fearon-Vogelstein model of how colorectal cancer develops step by step.

## Summary

Eric R. Fearon is Director of the Rogel Cancer Center and Emanuel N. Maisel Professor of Oncology at the University of Michigan. He is a molecular geneticist known as co-author of the Fearon-Vogelstein model describing how colorectal cancer develops step by step, and for cloning the DCC gene. His selected paper sets out a genetic model for colorectal tumorigenesis. He now directs the Rogel Cancer Center while continuing to study Wnt and APC signalling and tumour suppressor genes in colorectal cancer.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Director, Rogel Cancer Center; Emanuel N. Maisel Professor of Oncology
- Specialisms: Colorectal cancer genetics; Wnt/APC signalling; Tumour suppressor genes

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/Eric_Fearon
- Rogel Cancer Center: https://www.rogelcancercenter.org
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Fearon%20ER%5BAuthor%5D

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- institutions: [University of Michigan Rogel Cancer Center](https://onco.cc/institutions/michigan-rogel/)
- pathways: [Wnt / β-catenin](https://onco.cc/pathways/wnt/)
- key papers: [A genetic model for colorectal tumorigenesis](https://onco.cc/key-papers/paper-fearon-cell/), [Genetic alterations during colorectal-tumor development](https://onco.cc/key-papers/paper-vogelstein-genetic-alterations-colorectal-tumor-development-nejm-1988/)

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