# Douglas R. Lowy

Source: https://onco.cc/people/douglas-lowy/  
OnCo record `douglas-lowy` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Co-developed the HPV vaccine technology that is eliminating cervical cancer in vaccinated populations.

## Summary

Douglas R. Lowy is Principal Deputy Director of the National Cancer Institute, where he has also served as acting director. He is known for co-developing with John Schiller the virus-like particle technology underlying all licensed HPV vaccines, work recognised with the Lasker Award in 2017. His selected paper shows that the papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic. His work on HPV biology and vaccine development is the basis for the prevention of cervical cancer and HPV-related head and neck cancer in vaccinated populations.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Principal Deputy Director, National Cancer Institute
- Specialisms: HPV biology; Vaccine development; Cancer prevention

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/Douglas_R._Lowy
- NCI leadership: https://www.cancer.gov/about-nci/leadership
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Lowy%20DR%5BAuthor%5D

## Connected records

- cancers: [Cervical cancer](https://onco.cc/cancers/cervical/), [Head and neck squamous cell carcinoma](https://onco.cc/cancers/head-and-neck/)
- technologies: [HPV & HBV vaccination](https://onco.cc/technologies/hpv-vaccine/)
- drugs: [Nonavalent HPV vaccine](https://onco.cc/drugs/gardasil-9/)
- institutions: [Cancer Grand Challenges](https://onco.cc/institutions/cancer-grand-challenges/), [National Cancer Institute (NIH)](https://onco.cc/institutions/nci/), [NCI Center for Cancer Research (intramural programme)](https://onco.cc/institutions/nci-ccr/)
- people: [Ian Frazer](https://onco.cc/people/ian-frazer/)

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JSON: https://onco.cc/api/v1/entities/douglas-lowy.json