# Douglas A. Levine

Source: https://onco.cc/people/douglas-levine/  
OnCo record `douglas-levine` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Surgeon-scientist who led the TCGA endometrial cancer study that created today's four molecular subtypes.

## Summary

Douglas Levine led the TCGA integrated genomic characterisation of endometrial carcinoma, which defined the POLE ultramutated, microsatellite-unstable, copy-number-low and copy-number-high (p53-abnormal) subtypes now embedded in international guidelines and trials. He also co-led the TCGA ovarian cancer analysis and directs gynaecologic oncology at NYU Langone, where his laboratory studies the origins of high-grade serous cancer.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: endometrial; genomics; surgery
- Role: Director of Gynecologic Oncology, NYU Langone Perlmutter Cancer Center
- Specialisms: Gynaecologic oncology surgery; Endometrial cancer genomics; Ovarian cancer genomics; Translational research

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Levine%20DA%5BAuthor%5D%20endometrial%20genomic

## Connected records

- cancers: [Endometrial cancer](https://onco.cc/cancers/endometrial/), [Ovarian cancer](https://onco.cc/cancers/ovarian/)
- technologies: [Whole-exome & whole-genome sequencing](https://onco.cc/technologies/wes-wgs/)
- institutions: [Laura and Isaac Perlmutter Cancer Center at NYU Langone Health](https://onco.cc/institutions/nyu-perlmutter/)
- key papers: [TCGA Pan-Cancer Atlas: 10,000 tumours across 33 cancer types, classified by molecular features](https://onco.cc/key-papers/paper-tcga-pancancer-atlas-cell-2018/)

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