# Curis

Source: https://onco.cc/companies/curis/  
OnCo record `curis` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Curis is a United States-based biotechnology company running 2 late-stage cancer trials of Emavusertib in chronic lymphocytic leukaemia and primary CNS lymphoma.

## Summary

Curis, based in Lexington, MA, the United States, is a biotechnology company. Curis is a biotechnology company developing differentiated therapeutics for cancer patients, including an IRAK4 inhibitor in clinical development for haematologic malignancies. On ClinicalTrials.gov it is the lead sponsor of 2 recruiting or active phase 2 and phase 3 interventional cancer trials, testing Emavusertib in chronic lymphocytic leukaemia and primary CNS lymphoma. The largest, NCT03328078 (CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)), plans to enrol 152 participants. Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.

## Fields

- Kind: Company
- Last checked: 2026-09-11
- Also known as: Curis, Inc.
- Tags: ctgov-sponsor
- HQ: Lexington, MA
- Type: biotech
- Website: https://www.curis.com

## Sources

- Official website: https://www.curis.com
- ClinicalTrials.gov: trials led by Curis: https://clinicaltrials.gov/search?lead=Curis%2C%20Inc.

## Connected records

- cancers: [Chronic lymphocytic leukaemia](https://onco.cc/cancers/cll/), [Primary CNS lymphoma](https://onco.cc/cancers/primary-cns-lymphoma/)
- drugs: [Emavusertib](https://onco.cc/drugs/emavusertib/)
- trials: [A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies](https://onco.cc/trials/nct07271667/), [CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)](https://onco.cc/trials/nct03328078/)

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