# Cancer Research UK Manchester Institute

Source: https://onco.cc/institutions/cruk-manchester-institute/  
OnCo record `cruk-manchester-institute` (Institution). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The Cancer Research UK Manchester Institute sits beside The Christie; Caroline Dive's group pioneered small-cell lung cancer models grown from circulating tumour cells and leads the circulating tumour DNA work of TRACERx, and the institute anchors the Manchester Cancer Research Centre.

## Summary

Founded as the Paterson Laboratories of the Christie Hospital and renamed the Cancer Research UK Manchester Institute in 2013, the institute moved into the rebuilt Paterson Building in 2023 after the 2017 fire. Director Caroline Dive's group pioneered circulating tumour cell-derived explant models of small-cell lung cancer and leads the ctDNA work of TRACERx with the Crick, and the institute anchors the Manchester Cancer Research Centre partnership and the CRUK Lung Cancer Centre of Excellence with UCL. Other groups study cancer inflammation, systems oncology, skin cancer, leukaemia biology and drug discovery. Its position within The Christie's campus gives rapid translation into early-phase trials.

## Fields

- Kind: Institution
- Last checked: 2026-09-09
- Also known as: Paterson Institute for Cancer Research; CRUK MI; Paterson Building
- City: Manchester, GB
- Type: research-institute
- Website: https://www.cruk.manchester.ac.uk

## Sources

- Homepage: https://www.cruk.manchester.ac.uk
- Manchester Cancer Research Centre: https://www.mcrc.manchester.ac.uk

## Connected records

- cancers: [Acute myeloid leukaemia](https://onco.cc/cancers/aml/), [Melanoma](https://onco.cc/cancers/melanoma/), [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- fronts: [Diagnostics & Biomarkers](https://onco.cc/fronts/diagnostics/), [Drug Discovery Platforms](https://onco.cc/fronts/drug-discovery/)
- technologies: [Comprehensive genomic profiling](https://onco.cc/technologies/cgp/), [Liquid biopsy (ctDNA)](https://onco.cc/technologies/liquid-biopsy/), [MRD / molecular residual disease testing](https://onco.cc/technologies/mrd-testing/), [Patient-derived xenografts](https://onco.cc/technologies/pdx-models/)
- institutions: [Cancer Research UK](https://onco.cc/institutions/cruk/), [Greater Manchester Cancer Alliance](https://onco.cc/institutions/greater-manchester-cancer-alliance/), [The Christie NHS Foundation Trust](https://onco.cc/institutions/the-christie/), [The Francis Crick Institute](https://onco.cc/institutions/francis-crick/)
- terms: [Circulating tumour DNA (ctDNA)](https://onco.cc/terms/ctdna/)
- people: [Caroline Dive](https://onco.cc/people/caroline-dive/), [Fiona Blackhall](https://onco.cc/people/fiona-blackhall/), [Samra Turajlić](https://onco.cc/people/samra-turajlic/), [Tim Somervaille](https://onco.cc/people/tim-somervaille/)
- trials: [DETERMINE](https://onco.cc/trials/determine-trial/), [TARGET National](https://onco.cc/trials/target-national/)

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