# Cradle

Source: https://onco.cc/companies/cradle-bio/  
OnCo record `cradle-bio` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Cradle is a protein-engineering AI platform used by pharma to optimise antibodies and enzymes.

## Summary

Cradle, based in Amsterdam and Zurich, is a protein engineering AI platform used by pharmaceutical companies to optimise antibodies and enzymes. It runs generative models over protein sequences with wet-lab feedback and raised a 73 million dollar Series B in 2024. OnCo links it to de novo designed protein binders. Whether AI-optimised antibodies show measurable advantages in the clinic over conventionally engineered ones is the open question. The de novo protein binder page carries the wider field.

## Fields

- Kind: Company
- Last checked: 2026-09-08
- Tags: ai; protein-design
- HQ: Amsterdam / Zurich
- Type: ai-software
- Website: https://www.cradle.bio

## Sources

- Official website: https://www.cradle.bio

## Connected records

- fronts: [Drug Discovery Platforms](https://onco.cc/fronts/drug-discovery/)
- technologies: [AI-driven drug & target discovery](https://onco.cc/technologies/ai-drug-design/), [De novo designed protein binders](https://onco.cc/technologies/de-novo-protein-design/)

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JSON: https://onco.cc/api/v1/entities/cradle-bio.json