# Community oncology and site networks

Source: https://onco.cc/technologies/community-oncology-networks/  
OnCo record `community-oncology-networks` (Technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The clinics where most cancer patients are actually treated, increasingly organised into large networks that also run trials.

## Summary

In the US, over half of patients are treated in community practices organised by The US Oncology Network (McKesson), OneOncology (TPG/AmerisourceBergen), Florida Cancer Specialists, American Oncology Network, and hospital systems; Sarah Cannon Research Institute (HCA/McKesson JV) and NCI's NCORP bring trials to them. Vertical integration with distributors and payer models (Enhancing Oncology Model) shape drug choice and trial access.

## Fields

- Kind: Technology
- Status: standard-of-care
- Last checked: 2026-09-08
- Tags: supporting
- Principle: Networked practices share EHR, pathways, purchasing, and research infrastructure to deliver care close to home.
- Strengths: Access near home; Large trial-eligible populations
- Limitations: Variable adoption of new biomarker testing; Consolidation and drug-margin incentives

## Sources

- Unger: most patients never get the chance to join a cancer trial, and when offered, half say yes (JNCI: Journal of the National Cancer Institute 2019): https://doi.org/10.1093/jnci/djy221

## Connected records

- fronts: [Supportive Care & Survivorship](https://onco.cc/fronts/supportive-care/)
- technologies: [AI trial matching & clinical decision support](https://onco.cc/technologies/ai-trial-matching/), [Oncology EHR and real-world data platforms](https://onco.cc/technologies/oncology-real-world-data/)
- companies: [Cardinal Health Nuclear & Precision Health Solutions](https://onco.cc/companies/cardinal-health/), [Florida Cancer Specialists & Research Institute](https://onco.cc/companies/florida-cancer-specialists/), [McKesson / The US Oncology Network](https://onco.cc/companies/mckesson-us-oncology/), [OneOncology](https://onco.cc/companies/oneoncology/), [Sarah Cannon Research Institute](https://onco.cc/companies/sarah-cannon-research-institute/)
- institutions: [National Cancer Institute (NIH)](https://onco.cc/institutions/nci/)
- terms: [340B Drug Pricing Program](https://onco.cc/terms/340b-program/), [Accrual and enrolment](https://onco.cc/terms/accrual/), [Centralisation and high-volume centres](https://onco.cc/terms/centralisation/), [Step-up dosing (T-cell engagers)](https://onco.cc/terms/step-up-dosing/)
- key papers: [Unger: most patients never get the chance to join a cancer trial, and when offered, half say yes](https://onco.cc/key-papers/paper-unger-trial-participation-barriers-jnci-2019/)

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