# Christopher J. Sweeney

Source: https://onco.cc/people/christopher-sweeney/  
OnCo record `christopher-sweeney` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Led CHAARTED, which showed adding docetaxel to hormone therapy extends survival in newly metastatic prostate cancer.

## Summary

Christopher Sweeney (University of Adelaide; formerly Dana-Farber) was principal investigator of CHAARTED, the ECOG trial showing early docetaxel with androgen deprivation adds more than a year of survival in high-volume metastatic hormone-sensitive prostate cancer, and co-led ENZAMET (enzalutamide) with ANZUP. His work established treatment intensification at diagnosis as the standard approach. He now directs an immunogenomics institute in South Australia.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: prostate; trialist; ecog-acrin
- Role: Director, South Australian Immunogenomics Cancer Institute; Professor, University of Adelaide
- Specialisms: Metastatic hormone-sensitive prostate cancer; Docetaxel and androgen receptor inhibitors; Cooperative-group trials; Immunogenomics

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Sweeney%20CJ%5BAuthor%5D%20prostate%20docetaxel

## Connected records

- cancers: [Prostate cancer](https://onco.cc/cancers/prostate/)
- technologies: [Androgen deprivation & AR pathway inhibitors](https://onco.cc/technologies/androgen-deprivation/), [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- targets: [Androgen receptor](https://onco.cc/targets/androgen-receptor/)
- institutions: [South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide](https://onco.cc/institutions/saigenci-adelaide/)
- trials: [CHAARTED (E3805)](https://onco.cc/trials/chaarted/)
- key papers: [STOpCaP: docetaxel or bisphosphonates added to standard of care in hormone-sensitive prostate cancer, a systematic review and meta-analysis](https://onco.cc/key-papers/paper-vale-stopcap-docetaxel-bisphosphonates-lancet-oncol-2016/)

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