# Cedars-Sinai Cancer

Source: https://onco.cc/institutions/cedars-sinai-cancer/  
OnCo record `cedars-sinai-cancer` (Institution). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Los Angeles's largest non-profit hospital's cancer enterprise, known for bladder cancer biology, glioma immunotherapy and the Molecular Twin AI project.

## Summary

Cedars-Sinai Cancer unites the Samuel Oschin Comprehensive Cancer Institute with Cedars-Sinai's regional network across Los Angeles. Director Dan Theodorescu's laboratory showed in 2023 that loss of the Y chromosome in bladder cancer drives immune evasion and sensitivity to checkpoint blockade; Keith Black's neurosurgery programme pioneered dendritic cell vaccines for glioma; and the Molecular Twin initiative combines multi-omics and AI to model individual patients, starting with pancreatic cancer. The centre has strong kidney, prostate, lung and women's cancer programmes and a phase 1 unit, and is pursuing NCI designation.

## Fields

- Kind: Institution
- Last checked: 2026-09-09
- Also known as: Samuel Oschin Comprehensive Cancer Institute
- City: Los Angeles, CA, US
- Type: hospital
- Website: https://www.cedars-sinai.org/programs/cancer.html

## Sources

- Cedars-Sinai Cancer: https://www.cedars-sinai.org/programs/cancer.html
- Clinical trials: https://www.cedars-sinai.org/research/clinical-trials.html

## Connected records

- cancers: [Bladder & urothelial cancer](https://onco.cc/cancers/urothelial/), [Glioma & glioblastoma](https://onco.cc/cancers/glioblastoma/), [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/), [Renal cell carcinoma](https://onco.cc/cancers/rcc/)
- fronts: [AI & Computation](https://onco.cc/fronts/ai-computation/)
- technologies: [Digital twins and virtual control arms](https://onco.cc/technologies/digital-twins-trials/), [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- people: [Armando E. Giuliano](https://onco.cc/people/armando-giuliano/), [Mark B. Faries](https://onco.cc/people/mark-faries/), [Robert Figlin](https://onco.cc/people/robert-figlin/), [Stephen J. Freedland](https://onco.cc/people/stephen-freedland/)
- bottlenecks: [Data silos](https://onco.cc/bottlenecks/b-data-silos/)
- drugs: [Ivermectin](https://onco.cc/drugs/ivermectin/)
- trials: [Ivermectin with balstilimab or pembrolizumab in metastatic triple-negative breast cancer (Cedars-Sinai phase 1/2)](https://onco.cc/trials/nct05318469/)

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