# Caris Life Sciences

Source: https://onco.cc/companies/caris/  
OnCo record `caris` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Whole-exome and whole-transcriptome tumour profiling at scale, with a large real-world database.

## Summary

Caris Life Sciences, based in Irving, Texas, and listed as CAI after its 2025 IPO, performs whole-exome and whole-transcriptome tumour profiling at scale and holds a large real-world database. Its products are MI Profile, which combines exome and transcriptome sequencing, Caris Assure, a blood-based assay, and MI Cancer Seek, which received FDA approval in 2024. OnCo links it to comprehensive genomic profiling and whole-exome and whole-genome sequencing, and to ideas that every tumour genomic report should be machine-readable and should list open, nearby, matched trials. Whether whole-transcriptome data changes treatment decisions often enough to justify its cost over targeted panels is the open question. MI Cancer Seek has its own page.

## Fields

- Kind: Company
- Last checked: 2026-09-04
- HQ: Irving, TX
- Type: diagnostics
- Website: https://www.carislifesciences.com
- Ticker: CAI

## Sources

- Official website: https://www.carislifesciences.com

## Connected records

- fronts: [Diagnostics & Biomarkers](https://onco.cc/fronts/diagnostics/)
- technologies: [Companion diagnostics](https://onco.cc/technologies/companion-diagnostic/), [Comprehensive genomic profiling](https://onco.cc/technologies/cgp/), [Whole-exome & whole-genome sequencing](https://onco.cc/technologies/wes-wgs/)
- key papers: [Molecular characterization of KRAS wild-type tumors in patients with pancreatic adenocarcinoma](https://onco.cc/key-papers/paper-philip-kras-wild-type-pancreatic-ccr-2022/), [Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targets](https://onco.cc/key-papers/paper-weinberg-biliary-profiling-jgo-2019/)
- ideas: [Every tumour genomic report machine-readable and deposited nationally](https://onco.cc/ideas/idea-data-structured-genomic-reports/), [Every tumour sequencing report lists open, nearby, matched trials pulled live](https://onco.cc/ideas/idea-tr1-ngs-report-live-trial-match/)
- drugs: [MI Cancer Seek](https://onco.cc/drugs/caris-mi-cancer-seek/)

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