# Alice L. Yu

Source: https://onco.cc/people/alice-yu/  
OnCo record `alice-yu` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Led the trial proving that an anti-GD2 antibody improves survival in high-risk neuroblastoma.

## Summary

Alice Yu is Professor of Pediatrics at UC San Diego and an immunotherapy investigator with the Children's Oncology Group (COG). A paediatric oncologist specialising in neuroblastoma and anti-GD2 antibodies, she was study chair of COG ANBL0032, the randomised trial of ch14.18 (dinutuximab) with GM-CSF and IL-2 that established anti-GD2 immunotherapy in high-risk neuroblastoma. Her papers report the anti-GD2 antibody with GM-CSF, interleukin-2 and isotretinoin for neuroblastoma in the New England Journal of Medicine and the long-term follow-up of that phase III study in Clinical Cancer Research. Her work made a monoclonal antibody against GD2 part of paediatric immunotherapy.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Professor of Pediatrics, UC San Diego; Children's Oncology Group immunotherapy investigator
- Specialisms: Neuroblastoma; Anti-GD2 antibodies; Paediatric immunotherapy

## Sources

- Children's Oncology Group: https://childrensoncologygroup.org
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Yu%20AL%5BAuthor%5D
- Google Scholar: https://scholar.google.com/scholar?q=Alice%20L.%20Yu

## Connected records

- cancers: [Neuroblastoma (paediatric)](https://onco.cc/cancers/neuroblastoma/)
- technologies: [Monoclonal antibodies](https://onco.cc/technologies/monoclonal-antibody/)
- targets: [GD2 (disialoganglioside)](https://onco.cc/targets/gd2/)
- drugs: [Dinutuximab (ch14.18) / dinutuximab beta](https://onco.cc/drugs/dinutuximab/)
- companies: [Children's Oncology Group (COG)](https://onco.cc/companies/childrens-oncology-group/)
- trials: [COG ANBL0032](https://onco.cc/trials/anbl0032/)
- institutions: [UC San Diego Moores Cancer Center](https://onco.cc/institutions/ucsd-moores/)

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