# AL8326

Source: https://onco.cc/drugs/al8326/  
OnCo record `al8326` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

AL8326 is an experimental small-molecule drug from Advenchen Pharmaceuticals in phase 3 trials for small-cell lung cancer, non-small-cell lung cancer and renal cell carcinoma, with its target not yet stated publicly.

## Summary

AL8326 is a small-molecule drug developed by Advenchen Pharmaceuticals and Advenchen Laboratories Nanjing. Its molecular target is not stated in the ClinicalTrials.gov intervention record, and OnCo has not confirmed one from the sponsor's pipeline page. ClinicalTrials.gov describes the intervention as: 10mg/tablet, Oral administration, once daily. It is the investigational product in 3 recruiting or active industry-led phase 2 and phase 3 interventional cancer trials, including the phase 3 study NCT06247605 (A Phase IIII Study of AL8326 in Small Cell Lung Cancer), in small-cell lung cancer, non-small-cell lung cancer and renal cell carcinoma. The largest, NCT06247605, plans to enrol 243 participants with primary completion expected 2028-07. Status reflects the highest phase registered on ClinicalTrials.gov; no efficacy results are recorded here.

## Fields

- Kind: Treatment
- Status: phase-3
- Last checked: 2026-09-11
- Tags: pipeline; ctgov-ingest
- Modality: small molecule (structure undisclosed or not yet in PubChem)
- Mechanism: Mechanism not stated in the ClinicalTrials.gov record or on the sponsor's pipeline page.

## Sources

- ClinicalTrials.gov: trials of AL8326: https://clinicaltrials.gov/search?intr=AL8326
- Sponsor page: https://www.advenchen.com

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Renal cell carcinoma](https://onco.cc/cancers/rcc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- companies: [Advenchen Laboratories](https://onco.cc/companies/advenchen-laboratories/)
- trials: [A Phase IIII Study of AL8326 in Small Cell Lung Cancer](https://onco.cc/trials/nct06247605/)

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JSON: https://onco.cc/api/v1/entities/al8326.json