# Aimery de Gramont

Source: https://onco.cc/people/aimery-de-gramont/  
OnCo record `aimery-de-gramont` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Invented the FOLFOX regimen that anchors colorectal chemotherapy and founded the GERCOR and ARCAD trial groups.

## Summary

Aimery de Gramont (Paris) designed the infusional fluorouracil and oxaliplatin regimen known as FOLFOX, showed its benefit in the pivotal 2000 trial, and co-led MOSAIC and the IDEA collaboration on adjuvant duration. He founded the GERCOR cooperative group and the ARCAD database of pooled colorectal trials, which has reshaped endpoints and trial design in the disease.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: colorectal; chemotherapy; cooperative-group
- Role: Head of Medical Oncology, Institut Hospitalier Franco-Britannique; Founder, GERCOR and ARCAD
- Specialisms: Colorectal cancer; Chemotherapy regimens; Adjuvant therapy; Meta-analysis

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=de%20Gramont%20A%5BAuthor%5D%20oxaliplatin%20colorectal

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- key papers: [Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer (MOSAIC)](https://onco.cc/key-papers/paper-mosaic-oxaliplatin-adjuvant-colon-nejm-2004/)

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